A fascinating weekend of FA Cup action lies in store, with the famous old competition at the fifth round stage.
There are eight Premier League clubs remaining, joined by four from the Championship, two from League One and two from the National League.
Here's your guide to all eight fixture, along with details on where to catch the televised games.
The FA Cup returns this weekend with 16 teams competing in the fifth round
Manchester United lifted the trophy last season, beating Crystal Palace in the Wembley final
Burnley vs Lincoln City
12.30pm kick-off, Live on BT Sport 2
Lincoln's run to the last-16 has captivated the whole country, with the Championship scalps of Ipswich Town and Brighton taking them to this stage.
If they were to claim the giant-killing of Premier League side Burnley - who have an outstanding record at Turf Moor this season - they would become the first non-league club to reach the last eight since QPR in 1914.
Their brotherly managerial team of Danny and Nicky Cowley are overseeing an outstanding season, with Lincoln also top of the National League and closing in on a Football League return after six years away.
Lincoln City celebrate after their victory over Championship Brighton in the last round
Lincoln's Nathan Arnold scores the decisive goal in their third round replay with Ipswich
As Ipswich and Brighton discovered to their cost, Lincoln have a number of attacking weapons at their disposal, including bulldozer forward Matt Rhead and speedster Nathan Arnold, who scored the winner against Ipswich.
Although the Red Imps will be backed by 3,200 fans, it'll take something special to cause an upset at Turf Moor, where Burnley have taken 29 of their 30 Premier League points this season.
Nonetheless, Clarets manager Sean Dyche has warned against complacency, saying: 'There's not a divine right to win football matches, you have to earn everything you get.'
Shock potential: 3/10
Danny Cowley (right) and his brother and assistant Nicky pictured in their office
Huddersfield Town vs Manchester City
It's hard to gauge whether this Cup tie is a help or hindrance for Huddersfield Town.
They are pushing hard for promotion from the Championship, sitting just four points behind Brighton in second and play fellow contenders Reading on Tuesday night, so it could be seen as a distraction.
But their manager David Wagner, who has impressed greatly with his achievements this season, is 'hungry' for a shock and wants to test his Terriers team against one of the best sides in the country.
David Wagner is enjoying an excellent season with Huddersfield, who face Manchester City
With their Champions League last-16 tie with Monaco next week, it is likely that Pep Guardiola will make changes to his side though, City being City, they'll still have plenty of firepower at a sold-out John Smith's Stadium.
Watch out for the on-loan duo from Chelsea, Izzy Brown and Kasey Palmer, up front for Huddersfield as well as their leading scorer Elias Kachunga, on loan from Bundesliga side Ingolstadt.
Guardiola's City have fluctuated between being unplayable to a muddled mess at times this season and Huddersfield's best bet is to hassle them and allow no time on the ball.
Shock potential: 6/10
Sergio Aguero could lead the City forward line when they visit the John Smith's Stadium
Middlesbrough vs Oxford United
More than 3,200 yellow-shirted Oxford fans will make the long journey to Teesside to back the League One team against Middlesbrough on Saturday.
With Boro likely to rotate players as they continue to fight for their Premier League survival, there is a realistic chance of Oxford inflicting more north-east pain, having beaten Newcastle in the last round.
They have not reached the quarter-finals since 1964 and their coach Michael Appleton is determined it will be more than just a 'big day out' for their supporters.
Toni Martinez of Oxford United celebrates after scoring in their 3-0 win over Newcastle
With his side just two points above the relegation zone, Aitor Karanka is likely to have one eye on next weekend's vital clash with Crystal Palace, increasing the chances of an upset.
Oxford are in good form, as well, having won five games on the spin in all competitions prior to their midweek defeat to Southend.
Boro need to keep tabs on Kane Hemmings, the striker who has already scored five goals on their Cup run.
Shock potential: 6/10
Middlesbrough's Adam Clayton in action during their goalless draw with Everton
Millwall vs Leicester City
Bring a weakened team down to The Den at your peril. As Bournemouth and Watford have discovered, Millwall are well and truly up for the Cup this season.
Both made significant changes against the League One promotion chasers and paid the price and Neil Harris will be hopeful of making it a hat-trick against Leicester.
The reality is that the FA Cup is a big distraction for Claudio Ranieri and his relegation-threatened team and, with a Champions League tie in Sevilla in midweek, he's bound to make changes.
Steve Morison celebrates his late winning goal against Watford in the fourth round
'Our target is the Premier League, that is it. Of course we play in the FA Cup and Champions League and we want to do our best, but our aim is to be safe at the end,' said Ranieri.
Veteran goal-getter Steve Morison scored the winner against Watford and will now bring his physical presence to bear on Leicester's fragile defence.
Shock potential: 8/10
Wes Morgan and Jamie Vardy look dejected as Leicester City are beaten at Swansea
Wolverhampton Wanderers vs Chelsea
5.30pm kick-off, Live on BT Sport 2
With Chelsea purring under Antonio Conte and eight points clear at the top of the Premier League, they can now focus on 'doubling up' with the FA Cup as well.
They will understandably start as strong favourites against a Wolves team who are struggling in the Championship this season.
However, the Cup seems to have brought out the best in Paul Lambert's side, who have already eliminated two top-flight sides in Stoke and Liverpool.
Chelsea celebrate Pedro's goal in their Premier League draw at Burnley last Sunday
Wolves are sweating on the fitness of Nouha Dicko but their driving force, as at Anfield, could come from Helder Costa, their Portuguese midfielder signed permanently from Benfica in January.
Incidentally, if Wolves get a crowd of 30,111 or more, it will be Molineux's biggest attendance in 36 years.
Shock potential: 4/10
Andreas Weimann scores Wolves' second goal in their 2-1 fourth round win at Anfield
Fulham vs Tottenham Hotspur
2pm kick-off, Live on BBC One
An intriguing London derby at Craven Cottage where upwardly-mobile Fulham take on an out-of-sorts Tottenham.
Slavisa Jokanovic's side have remained in the Championship play-off picture with consecutive 3-2 wins over Wigan and Nottingham Forest, and were at their free-flowing best when they beat Hull in the fourth round.
With exciting attacking options at his disposal like Floyd Ayite, Chris Martin, Neeskens Kebano, Sone Aluko and Tom Cairney, Fulham should trouble Spurs, especially on their own patch.
Neeskens Kebano celebrates after scoring Fulham's winner in midweek against Forest
Mauricio Pochettino's Spurs have endured a bad week, losing to Liverpool in the Premier League and Gent in the Europa League, and Pochettino could well rotate a few of his big names.
Fulham hope this game will merely be an appetiser ahead of a return to the top-flight next season and it's a good chance to make a statement.
Shock potential: 7/10
Harry Kane is likely to be rested for Tottenham at Craven Cottage on Sunday afternoon
Blackburn Rovers vs Manchester United
4.15pm kick-off, Live on BT Sport 2
Manchester United's quest for success on four fronts continues at Ewood Park, where Jose Mourinho's side will be strong favourites despite likely resting their star names.
It's a busy spell for United, with this tie sandwiched between the two legs of their Europa League tie with Saint-Etienne and a week ahead of the EFL Cup final with Southampton, but they certainly have the squad to cope.
Zlatan Ibrahimovic celebrates his hat-trick in Man United's Europa League win over St Etienne
Things seem to be on an upward curve under Mourinho with United starting to look something like their old self, and they've been especially prolific in the Cup, beating Reading and Wigan 4-0.
Little hope for a Rovers side currently fighting for their Championship lives amid the constant off-field turbulence brought about by their ownership.
Sam Gallagher, the forward on loan from Southampton, and Danny Graham will be the ones to trouble United if anyone can.
Shock potential: 3/10
Danny Graham rues a missed chance during Blackburn's 1-1 draw at Rotherham
Sutton United vs Arsenal
7.55pm kick-off, Live on BBC One
Arguably the best has been saved until last during this FA Cup weekend with the biggest occasion seen at Sutton United's Gander Green Lane, well, ever.
The 5,000-capacity ground will be packed to the gills, with millions more tuned in to BBC One, to see if the National League side can beat Premier League giants Arsenal on their plastic pitch, which may or may not be a leveller.
Sutton's wins over AFC Wimbledon and Leeds United in previous rounds were the stuff of fairytales, so this would be in the realms of fiction. Think J.L Carr's classic 1975 novel 'How Steeple Sinderby Wanderers Won the F.A. Cup.'
Sutton United celebrates in their dressing room at Gander Green Lane after beating Leeds
As you'd imagine, Sutton don't have a transfer budget and their playing squad has been formed from a mixture of free agents, freebies and loanees, including four Arsenal academy graduates.
Arsenal's current travails, with Arsene Wenger under severe pressure following their humiliating Champions League defeat at Bayern Munich, have led more to subscribe to the tantalising possibility of an upset.
Surely they couldn't? Surely?
Shock potential: 2/10
Arsene Wenger is under immense pressure after Arsenal's 5-1 loss to Bayern Munich